Journal
PLANTA MEDICA
Volume 72, Issue 14, Pages 1334-1338Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-947256
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12,15-Epoxy-5 alpha H,9 beta H-labda-8(17),13-dien-19-oic acid (1) and 14-methoxy-15,16-dinor-5 alpha H,9 alpha H-labda-13(E),8(17)-dien-12one (2), two new labdane-type diterpenes, and 1 alpha-hydroxy-8,12-epoxyeudesma-4,7,11-triene-6,9-dione (3), one new eudesmane-type sesquiterpene, were isolated from Chloranthus henryi Hemsl, along with two known compounds, 8 beta H-eudesma-4(14),7(11)-dien-12,8-olide (4) and 80-hydroxyeudesma-4(14),7(11)-dien-12,8-olide (5). Their structures were established by a combination of 1D- and 2D-NMR spectroscopic techniques. The new compounds 2, 3 and the known compound 4 exhibited antitumor activities against Hela and K562 human tumor cell lines.
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