Journal
JOURNAL OF ANTIBIOTICS
Volume 59, Issue 11, Pages 720-723Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2006.96
Keywords
azaphilone; antifungal; antimicrobial; structure elucidation
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A new hydrogenated azaphilone Sch725680 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was achieved based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 64 mu g/ml, respectively.
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