Journal
NANO LETTERS
Volume 6, Issue 11, Pages 2630-2636Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl061666f
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- NIBIB NIH HHS [EB001956] Funding Source: Medline
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A spectroscopic assay based on surface enhanced Raman scattering (SERS) using silver nanorod array substrates has been developed that allows for rapid detection of trace levels of viruses with a high degree of sensitivity and specificity. This novel SERS assay can detect spectral differences between viruses, viral strains, and viruses with gene deletions in biological media. The method provides rapid diagnostics for detection and characterization of viruses generating reproducible spectra without viral manipulation.
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