Journal
TETRAHEDRON LETTERS
Volume 47, Issue 46, Pages 8025-8027Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.09.061
Keywords
solution-phase parallel synthesis; 1,2,4-triazoles; benzimidazoles
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A solution-phase synthesis for the preparation of substituted 2-(1,2,4-triazol-3-yl)benzimidazoles from triazole aldehydes and ortho-phenylenediamines has been developed for the purpose of producing diverse lead generation libraries. Crude products were obtained and further purified by mass-guided preparative HPLC. (c) 2006 Elsevier Ltd. All rights reserved.
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