Journal
TETRAHEDRON LETTERS
Volume 47, Issue 46, Pages 8087-8090Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.09.055
Keywords
tandem reactions; Michael reactions; Henry reactions; tetrahydrothiophenes
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In situ generated nitro alkenes underwent tandem Michael-Henry and Michael-Michael sequences leading to the 'one-pot' formation of 3,4-substituted tetrahydrothiophenes using the commercially available 1,4-dithiane-2,5-diol (the dimer of merca-ptoacetaldehyde) or its 4-mercapto-2-butenoates derivatives as suitable bifunctional partners, respectively. (c) 2006 Elsevier Ltd. All rights reserved.
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