4.4 Article

Convenient synthesis of N-(4-(2-aminopyridin-4-yl)thiazol-2-yl)-2-phenylacetamides

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 46, Pages 8079-8081

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.09.053

Keywords

2-aminopyridine; thiourea; thiazole; bromination; alpha-bromoketone

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We report a facile one-pot, three-step synthesis of N-(4-(2-aminopyridin-4-yl)thiazol-2-yl)-2-phenylacetamides via condensation of 2-p-methoxybenzylamino-4-acetylpyridine with phenylacetylthioureas. Published by Elsevier Ltd.

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