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New functions for Y family polymerases

Journal

MOLECULAR CELL
Volume 24, Issue 4, Pages 493-495

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2006.10.021

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Funding

  1. MRC [G0501450] Funding Source: UKRI
  2. Medical Research Council [G0501450] Funding Source: Medline
  3. Medical Research Council [G0300662B, G0501450] Funding Source: researchfish

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The Y family of DNA polymerases plays crucial roles in carrying out translesion synthesis past damaged bases in DNA. Several recent papers suggest that they might have other roles as well in gene conversion, in nucleotide excision repair (NER), and in DNA replication under stressed conditions.

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