Journal
INTERNATIONAL JOURNAL OF CARDIOLOGY
Volume 113, Issue 3, Pages 427-429Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijcard.2005.10.019
Keywords
Down syndrome; AOPP-CRP; atherosclerosis
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Murdoch et al. in 1977 called Down syndrome an atheroma-free model. In this preliminary study, we investigated advanced oxidation protein products (AOPP) ami high-sensitive C-reactive protein (hs-CR-P) in 47 age-matched Down syndrome patients and 20 age-matched healthy controls. In these healthy patients, we detected no new biochemical risk factors for atherosclerosis, such as AOPP and hs-CR-P, so risks are probably considerably lower. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
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