4.4 Article

Solvent-free facile synthesis of novel α-tosyloxy β-keto sulfones using [hydroxy(tosyloxy)iodo]benzene

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 47, Pages 8239-8241

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.09.107

Keywords

alpha-tosyloxy beta-keto sulfones; beta-keto sulfones; solvent-free synthesis; [hydroxy(tosyloxy)iodo]benzene

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A facile, general and high yielding protocol for the synthesis of novel alpha-tosyloxy beta-keto sulfones is described utilizing relatively non-toxic, [hydroxy(tosyloxy)iodo]benzene, under solvent-free conditions at room temperature. (c) 2006 Elsevier Ltd. All rights reserved.

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