Journal
TETRAHEDRON LETTERS
Volume 47, Issue 47, Pages 8267-8270Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.09.094
Keywords
bryostatin; chelation; allylation; stannane
Categories
Funding
- NIGMS NIH HHS [R01 GM028961, R01 GM028961-24, R01 GM028961-23] Funding Source: Medline
Ask authors/readers for more resources
An expeditious assembly of a C-1-C-16 Subunit of bryostatin I is described. A pyran annulation reaction was utilized to form the B-ring by reaction of a hydroxy-allylsilane with a fully elaborated A-ring subunit. This annulation process proceeded with complete diastereoselectivity and in excellent isolated yield despite the presence of potentially sensitive functionality in the A-ring segment. (c) 2006 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available