Journal
APPLIED CATALYSIS A-GENERAL
Volume 315, Issue -, Pages 147-149Publisher
ELSEVIER
DOI: 10.1016/j.apcata.2006.08.033
Keywords
huorapatite; zinc bromide; heterogeneous catalysis; 3-substituted indoles; Michael addition
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Fluorapatite doped zinc bromide was found to be a very efficient heterogeneous catalyst for the preparation of 3-substituted indoles from Michael addition of indoles to alpha,beta-unsaturated ketones in good to excellent yields. The substitution on the indole nucleus occurred exclusively at the 3-position. and N-alkylation products have not been observed. (c) 2006 Elsevier B.V. All rights reserved.
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