4.4 Article

Synthesis of dispirooxindolecycloalka[d]pyrimidino[2,3-b]-thiazole pyrrolidine/thiapyrrolizidine ring systems

Journal

TETRAHEDRON
Volume 62, Issue 48, Pages 11274-11281

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.09.008

Keywords

azomethine ylide; regioselective; spiropyrrolidines; spirothiapyrrolizidines

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The synthesis of a new class of spirooxindolo pyrrolidines and spirooxindolo thiapyrrolizidines has been accomplished by a three component, one-pot 1,3-dipolar cycloaddition reaction. The cycloaddition was found to be highly regioselective. (c) 2006 Elsevier Ltd. All rights reserved.

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