Journal
OCULAR IMMUNOLOGY AND INFLAMMATION
Volume 14, Issue 6, Pages 333-339Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/09273940600976938
Keywords
VKH; triple agent immunosuppression
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Purpose: To describe the role of triple agent immunosuppression in severe recalcitrant cases of Vogt-Koyanagi-Harada syndrome. Materials and methods: Retrospective chart review of five cases of Vogt-Koyanagi-Harada syndrome. Results: All cases were treated with oral prednisolone, azathioprine, and cyclosporine in combination, and rapid remission was observed in all patients. The synergistic effect of the triple agent immunosuppressives helped in preventing recurrences. Prolonged treatment with steroid sparing immunosuppressives in severe and recalcitrant cases of Vogt-Koyanagi-Harada syndrome maintained disease remission. Conclusion: Severe cases of Vogt-Koyanagi-Harada syndrome can be treated with early use of high-dose triple agent immunosuppressives.
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