4.5 Review

Hsp90 as a target for drug development

Journal

CHEMMEDCHEM
Volume 1, Issue 12, Pages 1331-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cmdc.200600112

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Funding

  1. NCI NIH HHS [CA109265] Funding Source: Medline
  2. NIGMS NIH HHS [P50 GM069663] Funding Source: Medline

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Heat shock protein 90 (Hsp90) has emerged as a promising target for the treatment of cancer, Alzheimer's and Parkinson's diseases, motor impairments, multiple sclerosis, and other disorders. Progress toward the development of both N and C-terminal inhibitors is described.

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