Journal
DRUG DISCOVERY TODAY
Volume 11, Issue 23-24, Pages 1061-1067Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2006.10.003
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From a direct comparison of the technical benefits of labelled reporter assays with the benefits of label-free assays, label-free appears to have significant advantages. Faster assay development times; accurate, high information content data; and less interference from labels. However, optical label-free platforms have not yet made a major impact in the drug discovery technology markets; are often viewed as having poor throughput, limited application; and are difficult to learn and use effectively.
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