Journal
HEMATOLOGICAL ONCOLOGY
Volume 24, Issue 4, Pages 189-195Publisher
WILEY
DOI: 10.1002/hon.788
Keywords
bone marrow; desmoplasia; fibrocytes; fibroblasts, myofibroblasts, EPCs; vasculo-genesis; angiogenesis
Categories
Ask authors/readers for more resources
In recent years the bone marrow has become recognized as a potential source of cells for nonhaematopoietic wound healing, in some instances demonstrating surprising plasticity in providing new epithelial cells. On the other hand, the contribution of bone marrow derived cells to fibrosis and blood vessel formation is more widely acknowledged. Tumour stroma has a vital role to play in determining cancer growth and spread, and there is a growing realization that the bone marrow has a significant input into this desmoplastic response. This review focuses on the contribution of bone marrow cells to tumour stroma, highlighting the bone marrow as a potential new portal through which to direct anti-tumour therapies. Copyright (c) 2006 John Wiley & Sons, Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available