Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 6, Issue 12, Pages 1357-1373Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955706778992996
Keywords
glycosylation; cancer; glycosyltransferase; synthesis; vaccine; immunotherapy; carbohydrate
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Tumor Associated Carbohydrate Antigens (TACAs) constitute powerftil tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.
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