Journal
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
Volume 16, Issue 4, Pages 397-406Publisher
SPRINGER
DOI: 10.1007/s10904-006-9065-4
Keywords
polyphosphazenes; water-soluble polymers; polymers for biomedical applications; vaccine immunoadjuvants; biodegradable polymers; drug delivery systems
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Water-soluble polyphosphazenes are an emerging class of biologically important synthetic polymers. Rapid advancements in the field have been facilitated with the discovery of potent polyphosphazene immunoadjuvants, use of hydrophilic polyphosphazenes in mild microencapsulation processes, and synthesis of water-soluble biodegradable polyphosphazenes - analogs of the well known pharmaceutical carriers. Present review summarizes the most recent advances in the synthesis of water-soluble polyphosphazenes, studies on their degradation and biological performance.
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