Journal
BIOTECHNOLOGY LETTERS
Volume 28, Issue 23, Pages 1909-1912Publisher
SPRINGER
DOI: 10.1007/s10529-006-9175-7
Keywords
biotransformation; common vetch; cyanohydrin; oxynitrilase; Vicia sativa L
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The defatted seed meal of common vetch (Vicia sativa L.) served as a source of (R)-oxynitrilase which catalyzed the enantioselective addition of HCN to aromatic, heteroaromatic, fluoro-substituted aromatic aldehydes to produce the corresponding enantiomeric pure cyanohydrins in yields of 52-100% and 88-99% ee at 12 degrees C under micro-aqueous medium (diisopropyl ether) without addition of buffer solution.
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