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The semenogelins:: proteins with functions beyond reproduction?

Journal

CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 63, Issue 24, Pages 2886-2888

Publisher

BIRKHAUSER VERLAG AG
DOI: 10.1007/s00018-006-6287-0

Keywords

semenogelin; zinc; fertility; seminal vesicle; kallikrein; reproduction

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The coagulum proteins of human semen, semenogelins I and II, are secreted in abundance by the seminal vesicles. Their function in reproduction is poorly understood as they are rapidly degraded in ejaculated semen. However, more recent results indicate that it is time to put the semenogelins in a broader physiological perspective that goes beyond reproduction and fertility.

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