Journal
AMERICAN JOURNAL OF PUBLIC HEALTH
Volume 96, Issue 12, Pages 2201-2208Publisher
AMER PUBLIC HEALTH ASSOC INC
DOI: 10.2105/AJPH.2005.065953
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Funding
- NCRR NIH HHS [M01 RR00042, M01 RR000042] Funding Source: Medline
- NIDDK NIH HHS [P60 DK020572, R18 DK062344, R18 DK 062344, 5P60 DK20572] Funding Source: Medline
- PHS HHS [R40 MC 00115-03] Funding Source: Medline
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Objectives. We assessed the influence of maternal anthropometric and metabolic variables, including glucose tolerance, on infant birthweight. Methods. In our prospective, population-based cohort study of 1041 Latino mother-infant pairs, we used standardized interviews, anthropometry, metabolic assays, and medical record reviews. We assessed relationships among maternal sociodemographic, prenatal care, anthropometric, and metabolic characteristics and birthweight with analysis of variance and bivariate and multivariate linear regression analyses. Results. Forty-two percent of women in this study entered pregnancy overweight or obese; at least 36% exceeded weight-gain recommendations. Twenty-seven percent of the women had at least some degree of glucose abnormality, including 6.8% who had gestational diabetes. Maternal multiparity, height, weight, weight gain, and 1-hour screening glucose levels were significant independent predictors of infant birthweight after adjustment for gestational age. Conclusion. Studies of birthweight should account for maternal glucose level. Given the increased risk of adverse maternal and infant outcomes associated with excessive maternal weight, weight gain, and glucose intolerance, and the high prevalence of these conditions and type 2 diabetes among Latinas, public health professionals have unique opportunities for prevention through prenatal and postpartum interventions.
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