Journal
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
Volume 11, Issue 4, Pages 346-352Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1529-8027.2006.00107.x
Keywords
amyloidoma; amyloidosis; lumbosacral plexopathy; MGUS; neuropathy; radiculopathy
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In this study, we present two cases of infiltrative, localized amyloidosis involving lumbosacral root and plexus, e.g., isolated amyloidomas. Rare and poorly understood amyloidomas may occur in both neurologic and non-neurologic tissues. The described cases emphasize potential for localized peripheral amyloidomas: (1) potential for associated lambda light chain lymphoplasmacytic lymphoma association; (2) e isolated amyloidosis without evidence for systemic plasma cell dyscrasia; (3) features suggestive of potential pathogenesis; and (4) discussion of treatment options including immunotherapy and resection. The limited literature and experience among other cases is described.
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