Journal
PHARMACOLOGY & THERAPEUTICS
Volume 112, Issue 3, Pages 810-832Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.pharmthera.2006.06.003
Keywords
phosphoproteins; postsynaptic; long-term potentiation; long-term depression; homeostatic plasticity
Categories
Funding
- NEI NIH HHS [R01 EY014882-01A1, R01 EY014882-02, R01 EY014882] Funding Source: Medline
Ask authors/readers for more resources
A number of neuronal functions, including synaptic plasticity, depend on proper regulation of synaptic proteins, many of which can be rapidly regulated by phosphorylation. Neuronal activity controls the function of these synaptic proteins by exquisitely regulating the balance of various protein kinase and protein phosphatase activity. Recent understanding of synaptic plasticity mechanisms underscores important roles that these synaptic phosphoproteins play in regulating both pre- and post-synaptic functions. This review will focus on key postsynaptic phosphoproteins that have been implicated to play a role in synaptic plasticity. (c) 2006 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available