Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 41, Issue 12, Pages 1439-1445Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2006.07.009
Keywords
antimicrobics; bromopyrroles; pyoluteorin analogs
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The synthesis and antimicrobial activity of new pyrrole derivatives structurally related to monodeoxypyoluteorin are described. The insertion of a keto or methylene spacer between the phenol group and the pyrroloyl moiety of brominated 2-(2'-hydroxybenzoyl)pyrroles leads to a decrease of the antibacterial activity. (c) 2006 Elsevier Masson SAS. All rights reserved.
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