Journal
MOLECULES
Volume 11, Issue 12, Pages 968-977Publisher
MDPI
DOI: 10.3390/11120968
Keywords
hyperbranched polymers; AB(2) monomers; DHICA; HIV-1; antiviral agents
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In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds.
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