Journal
PHYSIOLOGY
Volume 21, Issue -, Pages 380-387Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00019.2006
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Ca is critical in both the electrical and mechanical properties of cardiac myocytes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, there are significant alterations in how myocyte Ca is regulated, and these alterations are critical in dictating both contractile dysfunction and certain cardiac arrhythmias that are characteristic of heart failure.
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