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A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO

Journal

BRITISH JOURNAL OF HAEMATOLOGY
Volume 135, Issue 5, Pages 603-633

Publisher

WILEY
DOI: 10.1111/j.1365-2141.2006.06343.x

Keywords

inherited platelet disorders; platelet glycoproteins; thrombocytopenia; platelet receptors; platelet bleeding

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The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.

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