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Connexin 43 signalling and cardioprotection

Journal

HEART
Volume 92, Issue 12, Pages 1724-1727

Publisher

BMJ PUBLISHING GROUP
DOI: 10.1136/hrt.2005.066878

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Connexin (Cx) 43 is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium. The Cx43 proteins are central to the cardioprotection afforded by ischaemic preconditioning (IP). The specific role of mitochondrial Cx43 in protection by IP is reviewed.

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