Journal
SCIENCE
Volume 314, Issue 5805, Pages 1583-1585Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1131372
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Funding
- NIGMS NIH HHS [R37 GM029554] Funding Source: Medline
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The success of nanorobotics requires the precise placement and subsequent operation of specific nanomechanical devices at particular locations. The structural programmability of DNA makes it a particularly attractive system for nanorobotics. We have developed a cassette that enables the placement of a robust, sequence-dependent DNA robot arm within a two-dimensional (2D) crystalline DNA array. The cassette contains the device, an attachment site, and a reporter of state. We used atomic force microscopy to demonstrate that the rotary device is fully functional after insertion. Thus, a nanomechanical device can operate within a fixed frame of reference.
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