4.5 Article

Direct composition analysis of a dynamic library of imines in an aqueous medium

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2006, Issue 24, Pages 5441-5444

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200600859

Keywords

combinatorial chemistry; carbohydrates; imines; molecular recognition; self-assembly

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Dynamic Combinatorial Chemistry: Direct detection of imines in water and their adaptive re-equilibration in the presence of a target are possible by simple HPLC analysis. The equilibrating mixture is fixed by a fast drop in the pH during the analytical step. (C) Wiley-VCH Verlag GmbH & Co.

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