Journal
TETRAHEDRON
Volume 62, Issue 50, Pages 11821-11826Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.08.049
Keywords
functionalised epoxides; amino alcohols; sphingosines; phytosphingosines
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Starting from a single suitable functionalised epoxide, a highly efficient stereoselective synthesis of D-erythro-sphingosine and D-lyxo-phytosphingosine is described. The approach allows the formal preparation of all stereoisomers of these sphingoid structures. (c) 2006 Published by Elsevier Ltd.
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