Journal
BIOSENSORS & BIOELECTRONICS
Volume 22, Issue 5, Pages 633-638Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2006.01.020
Keywords
nickel; graphite; electroplating; biosensors; acetylcholine
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Pure nickel electrodes can be used as biosensors especially for sensing and estimating acetylcholine neurotransmitter. In the present work, a good electrochemical sensor was developed by electroplating nano nickel oxide reinforced nickel on graphite substrate. The morphology of the working electrode surface was studied by using a scanning electron microscope (SEM). The electrochemical and biological performance of the modified electrode was characterized by polarization studies in different media. The present modified electrode showed good sensing performance with a response time as low as 8 s during sensing and estimation of acetylcholine. The sensitivity of the modified electrode was 34.88 mu A/(mu M cm(2)). (c) 2006 Elsevier B.V. All rights reserved.
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