Journal
DRUGS
Volume 67, Issue 13, Pages 1947-1967Publisher
ADIS INT LTD
DOI: 10.2165/00003495-200767130-00015
Keywords
nitazoxanide; antiprotozoal; antihelminthic; tizoxanide; gastrointestinal infections; diarrhoea; pharmacodynamics; pharmacokinetics; therapeutic use tolerability
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Nitazoxanide (Alinia((R)), Daxon((R)), Dexidex((R)), Paramix((R)), Kidonax((R)), Colufase((R)), Annita((R))) has in vitro activity against a variety of microorganisms, including a broad range of protozoa and helminths. Nitazoxanide is effective in the treatment of protozoal and helminthic infections, including Cryptosporidium parvum or Giardia lamblia, in immunocompetent adults and children, and is generally well tolerated. Nitazoxanide is a first-line choice for the treatment of illness caused by C. parvum or G. lamblia infection in immunocompetent adults and children, and is an option to be considered in the treatment of illnesses caused by other protozoa and/or helminths.
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