Journal
NUTRITIONAL NEUROSCIENCE
Volume 10, Issue 3-4, Pages 129-135Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10284150701414046
Keywords
Parkinson's disease; diet; energy expenditure; levodopa
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Objective: To establish whether a diet based on the usage of low-protein products for renal patients (LPP) is associated with higher energy expenditure (EE) than a free low-protein diet (NO-LPP) by calculating 24 h EE by indirect calorimetry using an electronic armband monitor. Design: Randomized, cross-over, single-blind, pilot clinical trial performed comparing two different low-protein dietary regimens. Subjects: Forty-two days with LPP and 42 days with NO- LPP regimen in six patients with Parkinson's disease with levodopa. Methods: Monitoring patient response to two different nutritional schemes through indirect calorimetry (armband), BMI, Patient Global Improvement Scale. Results: Mean total EE was 1731 +/- 265 kcal/day with NO-LPP vs. 1903 +/- 265 kcal/day with LPP (p = 0.02). Conclusions: The usage of LPP increases EE and improves motor function in PD patients to a greater extent than NO- LPP dietary regimen. Calorie intake should be increased to prevent malnutrition in the long-term. Sponsorship: Fondazione Grigioni per il Morbo di Parkinson.
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