Journal
ANIMAL GENETICS
Volume 42, Issue 5, Pages 560-562Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1365-2052.2011.02183.x
Keywords
data cleaning; genome analysis; genotyping; linkage analysis; population genetics
Funding
- Biotechnology and Biological Sciences Research Council [BBS/B/05478/2]
- BBSRC [BBS/E/D/05191130] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/B/05478, BBS/E/D/05191130, BBS/B/05478/2] Funding Source: researchfish
Ask authors/readers for more resources
Datapoint errors in pedigree genotype data sets are difficult to identify and adversely affect downstream genetic analyses. We present GENOTYPECHECKER, a desktop software tool for assisting data cleansing. The application identifies likely data errors in pedigree/genotype data sets by performing an inheritance-checking algorithm for each marker across the pedigree, and highlights inconsistently inherited genotypes in an exploratory user interface. By 'masking' suspect datapoints and rechecking inheritance consistency, erroneous datapoints can be confirmed and cleansed from the data set. The software, examples and documentation are freely available at http://bioinformatics.roslin.ac.uk/genotypechecker.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available