Journal
ANIMAL GENETICS
Volume 43, Issue 1, Pages 104-107Publisher
WILEY
DOI: 10.1111/j.1365-2052.2011.02219.x
Keywords
goat; haplotype; linkage disequilibrium; polymorphisms
Funding
- National 863 Program of China [2007AA10Z167]
- '13115' Sci-Tech Innovation Programme of Shaanxi Province [2009ZDKG-19]
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This study reported the analysis of KIT ligand (KITLG) gene polymorphisms in 681 goats of three breeds: Xinong Saanen (SN), Guanzhong (GZ), and Boer (BG). In addition, the study identified three allelic variants: g.769T>C and g.817G>T in SN and GZ breeds, and g.9760G>C in the three goat breeds. The g.769T>C and g.817G>T loci were closely linked (r2 > 0.33). All the single nucleotide polymorphism loci were in HardyWeinberg disequilibrium (P < 0.05). Significant associations were found for litter size with all three loci. Therefore, these results suggest that the KITLG gene is a strong candidate gene affecting litter size in goats.
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