Journal
NEUROIMAGE
Volume 34, Issue 1, Pages 144-155Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2006.09.018
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Funding
- Medical Research Council [G0501316] Funding Source: researchfish
- MRC [G0501316] Funding Source: UKRI
- Medical Research Council [G0501316] Funding Source: Medline
- Wellcome Trust [078204] Funding Source: Medline
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We present a direct extension of probabilistic diffusion tractography to the case of multiple fibre orientations. Using automatic relevance determination, we are able to perform online selection of the number of fibre orientations supported by the data at each voxel, simplifying the problem of tracking in a multi-orientation field. We then apply the identical probabilistic algorithm to tractography in the multi- and single-fibre cases in a number of example systems which have previously been tracked successfully or unsuccessfully with single-fibre tractography. We show that multi-fibre tractography offers significant advantages in sensitivity when tracking non-dominant fibre populations, but does not dramatically change tractography results for the dominant pathways. (c) 2006 Elsevier Inc. All rights reserved.
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