Journal
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL
Volume 92, Issue 1, Pages 131-132Publisher
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.10455
Keywords
thalassemia; iron overload; MRI; cardiac R2*
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Recent advances in magnetic resonance imaging (MRI) techniques allow the assessment of iron overload in tissues' especially the heart 2 in transfusion-dependent thalassemia patients. The R2* value (1/T2*) recorded in the intraventricular septum of the heart indirectly measures the degree of cardiac iron load. Applying this new technology we looked at a number of historical and biochemical parameters in order to determine their relationship to cardiac iron overload and the effect of cardiac iron on functional and structural changes of the heart in transfusion-dependent thalassemics.
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