Journal
AMERICAN JOURNAL OF SURGERY
Volume 210, Issue 5, Pages 911-921Publisher
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjsurg.2015.03.021
Keywords
Sex; Sex hormone; Trauma; Prognosis
Categories
Funding
- National key Technology RD Program [2012BAI11B00]
- National Nature Science Foundation of China [81271348]
- Hubei Province's Outstanding Medical Academic Leader Program
- Hubei Science and Technology Key Project [2013CFA075]
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BACKGROUND: This study aims to assess the influence of sex on outcomes among trauma patients, including injury severity, medical resource utility, complications, and mortality. METHODS: A systematic review of the literature was conducted by internet search. Data were extracted from selected studies and analyzed using Stata to compare outcomes between male and female injured patients. RESULTS: Eventually, 19 studies met our inclusion criteria with 100,566 men and 39,762 women. Pooled data revealed that male sex was associated with increased risk of mortality, hospital length of stay, and higher incidence of complications. No difference was detected in injury severity between male and female patients. CONCLUSION: Evidence of this meta-analysis strongly supports the sex dimorphism in the prognosis of trauma patients and further work should be done to decipher potential mechanism. (C) 2015 Elsevier Inc. All rights reserved.
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