Age-related changes in the normal sagittal relationship between globe and orbit

Purpose: To establish the pattern of change in globe protrusion with advancing age. The findings contribute to our understanding of orbital ageing, and are useful in the longitudinal assessment of patients with orbital disease, craniofacial abnormalities and trauma. Methods: Ocular protrusion from the lateral orbital rim to the corneal, apex was measured in 653 Caucasians aged 21-80 years. Healthy subjects only were included in the study excluding those with ocular or orbital diseases. Measurements were taken using a single instrument and observer. Data were analysed for both sexes and each eye separately. Results: The mean exophthalmometry reading in both sexes (318 femate and 335 mate) was 19 2 mm. Ninety-eight percent of readings between the two eyes were within 1 mm of each other and no subject had greater than 2 mm of asymmetry. In all. groups there was a negative linear correlation between ocular protrusion and age. This correlation was found to be highly statistically significant in all. groups (r=0.56-0.65, p < 0.0001). There was no statistically significant difference between change in ocular protrusion with age between the left and right eye for females or mates. This study demonstrates a strong association between ocular protrusion and age in a Caucasian population. This association is an almost linear reduction in ocular protrusion with increasing age between the ages of 31 and 80. Asymmetry in ocular protrusion between the two eyes does not develop with increasing age. (c) 2006 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Pubtished by Elsevier Ltd. All rights reserved.