Influence of pectin and guar gum composite flour on plasma biochemical profile of streptozotocin-induced diabetic male albino rats

Dietary fiber sources like pectin and guar gum have gained immense importance because of their constructive role of releasing sugars and absorbing sugars slowly in the intestinal tract; consequently, they reduce the severity of diabetes mellitus. In this article, we explore the hypoglycemic and hypocholesterolemice worths of pectin and guar gum by adding them to wheat flour to prepare chapaties, a staple in the diet of those in the Indo-Pak region. For this purpose, four different treatments of composite flour were prepared by adding wheat flour with 3% pectin (T-1), 3% guar gum (T-2), a combination of pectin and guar gum 2% of each (T-3), along with a control (T-0). Composite flour samples were stored for 60 days and analyzed for proximate analysis on monthly basis. Protein and fat contents of different treatments were affected significantly by various storage intervals. Likewise, chapaties were prepared after every storage interval and evaluated for sensoric attributes. Chapaties prepared from treatment T-2 gained highest score with respect to all sensory parameters (color, flavor, taste, texture, chewing ability, and fold ability) followed by T-0, T-3, and T-1. The chapaties prepared from composite flour samples were fed to Streptozotocin-induced diabetic male albino rats to find out their impact oil plasma biochemical profile. After decapitating the rats, tire blood sample was collected and analyzed for blood glucose, total cholesterol, and triglycerides level. Rats fed oil T-2, showed highest reduction (17.09%) in blood glucose followed by T-1 (10.25%) and T-3 (9.24%), as compared to T-0. Blood cholesterol was reduced up to 18.88, 16.76, and 12.23% by T-2, T-3, and T-1, respectively than that of control. Similarly, T-2 showed the highest reduction (16.33%) in blood triglyceride level followed by T-3 (12.31%) and T-1 (2.76%). We concluded front our research study that dietary fibers front guar gum and pectin are helpful ill reducing blood glucose and cholesterol levels. It is further suggested that guar gum is more effective than pectin to control these diseases. For this reason, wheat flour should be supplemented with dietary fiber sources to combat the existing dilemma of diabetes and hypercholesterolemia.