Journal
CLINICAL NEUROLOGY AND NEUROSURGERY
Volume 109, Issue 1, Pages 54-57Publisher
ELSEVIER
DOI: 10.1016/j.clineuro.2006.01.009
Keywords
14-3-3; glutamic acid decarboxylase antibody; CJD; cerebellar ataxia; anti-GAD65
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Funding
- NCRR NIH HHS [M01 RR00079] Funding Source: Medline
- NIA NIH HHS [AG16570, K23 AG021989-01, AG10129, P50 AG023501, P50-AG05142] Funding Source: Medline
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In a patient with a rapidly progressive neurological condition with ataxia and cognitive complaints, Creutzfeldt-Jakob disease (CJD) is often high in the differential, particularly when there is an elevated CSF 14-3-3 protein level. We present a case of anti-glutamic acid decarboxylase antibody (anti-GAD65) positive cerebellar ataxia associated with cognitive complaints and elevated CSF 14-3-3 protein. (c) 2006 Elsevier B.V. All rights reserved.
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