4.2 Article

Regioselective nucleophilic opening of epoxides and aziridines under neutral conditions in the presence of β-cyclodextrin in water

Journal

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
Volume 261, Issue 1, Pages 1-5

Publisher

ELSEVIER
DOI: 10.1016/j.molcata.2006.07.040

Keywords

epoxide; sodium cyanide; beta-hydroxy nitrile; N-tosyl aziridines; beta-amino alcohols; beta-cyclodextrin; supramolecular catalysis water

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A variety of beta-hydroxy nitriles and beta-amino alcohols have been synthesized by the regioselective ring opening of epoxides and aziridines under neutral and aqueous conditions in the presence of beta-cyclodextrin in good yields. (c) 2006 Elsevier B.V. All rights reserved.

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