4.8 Article

Iridium-catalyzed conversion of alcohols into amides via oximes

Journal

ORGANIC LETTERS
Volume 9, Issue 1, Pages 73-75

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol062549u

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The iridium catalyst [Ir(Cp*)Cl-2](2) is effective for the rearrangement of oximes to furnish amides. The reaction has been combined with catalytic transfer hydrogenation between an alcohol and alkene to allow the conversion of alcohols into amides in a one-pot process.

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