Journal
JOURNAL OF BIOTECHNOLOGY
Volume 127, Issue 3, Pages 503-507Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jbiotec.2006.07.013
Keywords
Bacillus subtilis 168; ituim A; biofilm fermentation; itu operon
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Bacillus subtilis 168 produces thin and fragile biofilm in the static culture, however, it was found out that its transformant B. subtilis RM/iSd 16 containing wild sfp, itu operon and degQ, which produced lipopeptide antibiotic iturin A, produced thick and much stable biofilm. Production of iturin A by RM/iSd16 in biofilm was almost two times higher compared to that in the submerged culture at 28 degrees C. (c) 2006 Elsevier B.V. All rights reserved.
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