4.5 Article

Electrospun poly(vinylidene fluoride)/poly(aminophenylboronic acid) composite nanofibrous membrane as a novel glucose sensor

Journal

ANALYTICAL BIOCHEMISTRY
Volume 360, Issue 2, Pages 189-195

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ab.2006.09.021

Keywords

glucose; amperometric sensor; fibrous membrane

Funding

  1. National Research Foundation of Korea [과06B1508] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Electrospinning was used to prepare the nanofibrous membrane (NFM) of the composite comprising poly(vinylidene fluoride) and poly(aminophenylboronic acid) (PVdF/PAPBA-NFM). The PVdF/PAPBA-NFM displayed an excellent linear response to the detection of glucose for the concentration range of I to 15 mM with a response time of less than 6 s. Further experiments on amperometric sensing of glucose were performed in the presence of interferents such as uric acid, ascorbic acid, acetaminophen, fructose, mannose, etc. using PVdF/PAPBA-NFM. The interferents did not. give significant overlapping current signal during the determination of glucose. Also, PVdF/PAPBA-NFM possesses better reproducibility toward glucose detection and storage stability. (c) 2006 Elsevier Inc. All rights reserved.

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