Journal
TETRAHEDRON LETTERS
Volume 48, Issue 3, Pages 371-375Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.11.083
Keywords
iridium; borylation; CH-activation; indole
Categories
Ask authors/readers for more resources
The selective CH-functionalization of 2-substituted indoles is presented. Using bis(pinacolato)diboron (2) in the presence of iridium complexes, a novel catalytic mono-borylation is observed preferentially at the 7-position of the indole. This allows for an efficient synthesis of various 2,7-di- and 2,4,7-trisubstituted indoles, which are otherwise difficult to access. The scope and limitation of the method is demonstrated. (c) 2006 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available