4.8 Article

Total synthesis of bistramide A

Journal

ORGANIC LETTERS
Volume 9, Issue 2, Pages 327-330

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol062957y

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Funding

  1. NCI NIH HHS [CA56304] Funding Source: Medline

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[GRAPHIC] An asymmetric synthesis of the marine metabolite bistramide A is reported. The synthesis relies on the utility of three different organosilane reagents to construct all principle fragments and 8 of the 11 stereogenic centers of the natural product.

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