Journal
ORGANIC LETTERS
Volume 9, Issue 2, Pages 315-318Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol062816w
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[GRAPHIC] A water-soluble fluorescent zinc sensor which binds strongly to Zn2+ (log K = 12.4) was successfully synthesized under physiological conditions. This sensor exhibits a good fluorescence response to Zn2+ over a wide pH range in water. Under the same conditions, several metal ions commonly present in a physiological environment, such as Na+, K+, Ca2+, Mg2+, Mn2+, Fe2+, and Co2+, showed little interference to the fluorescence response to Zn2+.
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