4.4 Article

Tandem Michael/Michael reactions mediated by phosphines or aryl thiolates

Journal

TETRAHEDRON
Volume 63, Issue 5, Pages 1100-1106

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.11.064

Keywords

tandem reactions; Michael additions; phosphines

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Tri-n-butyl phosphine was found to effect tandem Michael/Michael cyclisations leading to the formation of cyclopentenes and cyclohexenes in good yields, whilst p-TolSH in conjunction with a catalytic amount of p-TolSNa effected cyclisation to the corresponding cyclopentanes and cyclohexanes. (c) 2006 Published by Elsevier Ltd.

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